This amplification could lead to greater reductions in your blood pressure than expected, possibly inducing a state of hypotension. For this reason, serious allergic reactions to most ubiquinol supplements are uncommon. ANSWER: While most people tolerate coenzyme Q10 well, it can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, and diarrhea. To rule out allergies and/or sensitivities to ingredients, a person could try ubiquinol supplements from a supplier with different additives than their current. Furthermore, if ubiquinol makes you feel more anxious than usual, the anxiety may have primed your sympathetic nervous system, causing you to sweat more frequently. It is unknown as to how ubiquinol affects the neuroendocrine system of persons without amenorrhea, however, it is possible that it significantly modulates hormone levels. It is possible that the majority of “side effects” reported by those supplementing may be unrelated to ubiquinol itself. Then again, some slight dizziness could be a transient reaction to ubiquinol that eventually subsides as your body adapts to supplementation. Took 100 mg daily on doctor’s advice for slight carotid artery blockage. Note:  For a majority of individuals, ubiquinol supplementation will not cause any side effects nor adverse reactions. © MentalHealthDaily.com 2013-2019 | Privacy Policy | Legal Notice | Affiliate Disclosure, Belviq (Lorcaserin) Side Effects & Adverse Reactions (List), Naltrexone Side Effects & Adverse Reactions (List), L-Tyrosine Side Effects & Adverse Reactions (List), Kratom Side Effects & Adverse Reactions (List), Phentermine Side Effects & Adverse Reactions (List), Magnesium Deficiency Symptoms, Causes, & Treatments, Probiotics Side Effects & Adverse Reactions (List), Pantoprazole (Protonix) vs. Omeprazole (Prilosec), Lexapro (Escitalopram) vs. Prozac (Fluoxetine), Pregabalin (Lyrica) vs. Gabapentin (Neurontin). In the meantime, you may want to rule out potential interactions, contraindications, sensitivities, and allergies to the ingredients within your supplement. We compare the side effects and drug effectiveness of Ubiquinol and Aspirin. Common flu-like symptoms that may emerge in a small percentage of ubiquinol users include:  chills, dizziness, fatigue, fever, headaches, muscle aches, nausea, and/or vomiting. While most people tolerate coenzyme Q10 well, it can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, and diarrhea. Interestingly, some that have documented tiredness while taking ubiquinol report feeling better when taking CoQ10 (ubiquinone). Ingredients within ubiquinol supplements to consider as potential triggers for allergies include: natural colorings, polysorbate 80, soy lecithin, and various types of oils. I am so confused. RashUbiquinol is processed by the liver and eliminated through bile. As a result, the antihyperglycemic agent may end up reducing blood sugar to a lower level than expected, leading to emergence of hypoglycemia (low blood sugar). Follow all directions on the product label and package. For example, if you’re taking a stack of supplements to enhance mitochondrial function such as: PQQ, creatine, acetyl-l-carnitine, alpha-lipoid acid, and others – the synergistic energy increase may be overwhelming enough to keep you awake at night. It also might lower blood pressure, so check your blood pressure carefully if you CoQ10 is a natural antioxidant, and both forms of CoQ10—ubiquinol and ubiquinone —are considered safe with few side effects. That said, you might also want to ensure that the ubiquinol isn’t somehow reducing your blood pressure (inducing a state of mild hypotension) whereby you could become sleepier than usual. Included below is a list of side effects that have been reported by a subset of ubiquinol users. If you’re feeling more keyed up and anxious while taking ubiquinol, the easiest solution is decreasing the dose to a level that makes you feel calm and/or able to function without excessive energy. It is possible that your ubiquinol might contain beeswax, gluten, nuts, and/or soy to provoke an adverse reaction. That said, it is possible that your blood pressure might fluctuate unpredictably as a ubiquinol side effect such as by slightly increasing, modestly decreasing, or exhibiting a combination of increases then decreases until the body adapts to its effect. It should be speculated that individuals with underlying neuropsychiatric disorders (especially anxiety disorders) may be more sensitive to neurological and biological changes induced by the ubiquinol, ultimately increasing proneness to an anxiogenic reaction. CoQ10 supplements appear to be safe and to produce few side effects when taken as directed.Mild side effects might include: 1. ), gluten/wheat, and soy. Any modulation of hormone concentrations could lead to unwanted side effects in both men and women. In fact, many ubiquinol users will question whether it’s really doing much of anything – because they don’t notice any change in their functioning after supplementation. Ubiquinol supplementation led to a 1.5-fold increase in the amount of CoQ10 in the blood. Taking 300 mgs of ubiquinol for 3 months my doctor called 911 because my heart was beating fast and irregular! On the other hand, you may experience sleepiness regardless of the ubiquinol supplement ingredients, especially if you’re a new user. Preliminary research suggests that ubiquinol supplementation may prove useful as an intervention for age-related illness, chronic fatigue syndrome, fibromyalgia, immune dysfunction, mitochondrial disorders, nerve pain, neurodegenerative disorders, and obesity. Ubiquinol supplements are emulsified in an oil-based agent such as MCT oil which may irritate the GI tract, cause stomach aches, and ultimately diarrhea – especially in newer users. Additionally, you may want to consider asking your doctor about safe, adjunctive intervention for managing ubiquinol-induced headaches. If the dizziness cannot be attributed to blood pressure or blood sugar fluctuations, it could be related to an allergy or sensitivity to ubiquinol or one of its constituents. Furthermore, it is a smart idea to track blood pressure, especially considering that ubiquinol might reduce your blood pressure to a state of subclinical hypotension, perhaps an explanation for feeling tired. Sleepiness: Though unusual as a side effect, sleepiness has been reported by some ubiquinol users as a reaction to their supplementation. To manage the nausea, you may want to try taking ubiquinol after eating a large meal and avoid administering it along with other drugs or supplements. There’s a chance that, at high doses, ubiquinol could alter gastric motility and expedite the flow of food through the GI tract to provoke a diarrheal response. Then again, you may want to consider that sweating you perceive as a side effect of ubiquinol may be nothing more than a correlation rather than a byproduct of its usage. Side Effects. I stopped taking it for a few days now my heart is beating normal!! Irritability: Only a few reports have been documented in which individuals experience irritability after supplementing with ubiquinol. But even in its oxidized form as ubiquinone, it may still have some antioxidant effect [1, 9].The membrane that surrounds cells contains fats that help keep it stable. Diarrhea: A disconcerting adverse reaction to ubiquinol that a small subset of users experience is diarrhea or abnormally loose stools. Further information The onset of flu-like symptoms after taking ubiquinol should be interpreted as an incompatibility between your body and the supplement you’re using, hence the reason you’re feeling sick. Anxiety: Although ubiquinol is understood to enhance energy levels, some individuals report experiencing such a significant energy spike, that it causes them to feel anxious. Things like how long the ubiquinol was sitting in a warehouse, storage conditions, possible contamination, and/or date until expiration should be taken into consideration. Rashes 8. What was the most noticeable or pronounced side effect that you endured during ubiquinol supplementation? For example, you may notice onset of fatigue or experience a headache in reaction to ubiquinol supplementation, whereas another person using the same supplement might not notice any unusual reaction. Examples of added ingredients to which you might be sensitive include:  colorings, gelatins, oils, soy, glycerin, beeswax, etc. By making slight tweaks to administration details, some users will report fewer side effects. Although professionals consider ubiquinol supplementation to be extremely safe for most adults, rare adverse effects can occur, including: allergic reactions, appetite loss, diarrhea, headache, nausea, and stomach aches. There’s no convincing evidence that ubiquinol itself is likely to cause flu-like symptoms in most people, especially when used at medically-recommended amounts. In the aforestated hypothetical scenario, it is likely that individual factors such as: a person’s age, co-administered substances, dietary intake of ubiquinol, genetics, and medical conditions – influenced the individually-distinct side effects experienced while taking ubiquinol. Note: A majority of ubiquinol supplements are devoid of dairy products (milk/egg-related), fish byproducts, nuts (e.g. I have had heart palpitations but I also felt those might be the result of the anxiety and stress I have felt after being diagnosed with carotid artery disease. IrritabilityThe safety of use of CoQ10 during pregnancy and breast-feeding hasn't been established. Other possible reasons for appetite reduction could be increased anxiety levels and/or hormone changes, each of which might cause a person to feel full and/or decrease desire to eat. eHealthMe makes it possible for everyone to … The study is created by eHealthMe based on reports (from sources including the FDA) of 599,962 people who take Ubiquinol and Aspirin, and is updated regularly. If ubiquinol is capable of altering hormone secretion and/or concentrations, most theorize that it’s likely to promote healthy hormone levels. CoQ10, in its ubiquinol form, is a strong antioxidant that protects the cell and mitochondrial membranes. Tests have concluded that high doses, such as 3600 mg of ubiquinone daily, are non-toxic to healthy and ill individuals, but may cause side effects, associated with diarrhea and abdominal discomfort. On a scale of 1 to 10, with 1 being negligible and 10 being severe, what numeric rating would you assign to the side effects you experienced from ubiquinol? Any reduction in appetite experienced while taking ubiquinol may be related to increases in energy levels from supplementation. It’s also possible that ubiquinol could induce sweating via an interaction with another substance (drug or supplement) or hormonal modulation. You may report them to the FDA. Your best bet is to thoroughly evaluate the ingredients list of any ubiquinol supplement before purchasing to rule out possible allergies. The overstimulation effect may be associated with increased activity within the sympathetic branch of the autonomic nervous system, leading some individuals to experience palpitations or abnormal changes in heart rhythms. In the event that you experience hypotension, a myriad of symptoms may emerge including:  dizziness, lightheadedness, nausea, and/or fainting. If you start taking ubiquinol and experience dizziness, there’s a chance that you may have initiated supplementation at too high of a dose. I am on blood pressure medicine! Blood pressure changes: Some individuals might experience changes in blood pressure as a side effect of supplementing with ubiquinol. I couldn't find any side effect like yeast or ovarian pain for Ubiquinol … I experienced profound exhaustion and severe shoulder, hip, leg and neck pain. For example, a small amount of medium-chain triglycerides are included within some preparations, and one side effect of MCT oil is anxiety. I returned it and ordered 50 mg. capsules so I can titrate up gradually. Has anyone experienced this before? After switching back to regular CoQ10, ubiquinone, that went away completely. Understand that although ubiquinol is regarded as extremely safe, you should always listen to your body and discuss side effects you’re experiencing with a doctor. Logically, this makes sense as ubiquinol is used to increase heart rate, resulting in improved blood flow and thus elevated athletic performance. It is possible that you could experience insomnia from ubiquinol supplementation, especially if you find that it significantly increases your energy levels and/or provokes anxiety. Note: The author of this site is not engaged in rendering professional advice or services to the individual reader. If the tiredness abates over the course of a few weeks, it was probably triggered by an ingredient-related sensitivity. To accurately know whether the ubiquinol is causing you to sweat, stop taking it for awhile and monitor your sweat production to determine whether it decreases; if it does, then you can be sure it was related to your ubiquinol. Heart palpitations: An odd reaction to ubiquinol that has been anecdotally reported in a small number of cases is heart palpitations. Loss of appetite 5. You, as a reader of this website, are totally and completely responsible for your own health and healthcare. If you feel more anxious than usual while taking ubiquinol or notice that your energy levels have skyrocketed, but also experience headaches, you may want to scale back on your dose and/or make an effort to upregulate parasympathetic activation to counteract the sympathetic-mediated vasoconstriction. Stop using ubiquinone and call your healthcare provider at once if you have: very low blood pressure--dizziness, severe weakness, feeling like you might pass out. I also may switch brands to see if that helps. Assuming you’re similar to the majority of ubiquinol users and are benefitting from its supplementation, continued usage is a smart option. Stomach aches: A side effect that may occur among those supplementing with ubiquinol is stomach aches. A majority of individuals supplementing with ubiquinol on a daily basis won’t experience any noticeable or unwanted side effects. If the flu-like symptoms persist regardless of modifications you make to dosing and/or the supplier – you may need to accept that ubiquinol isn’t a good fit for your biology. More clinical trials have been conducted with ubiquinone than ubiquinol. Nausea: A side effect of ubiquinol that has been reported is nausea, characterized by feeling sick as if you’re on the verge of vomiting. I took 1 200 mg. capsule of a famous brand of ubiquinol and had a severe reaction which lasted 6 or 7 hours. The ideas, procedures, and suggestions contained within this work are not intended as a substitute for consulting with a medical doctor. To counteract the occurrence of fatigue, you may want to try taking your ubiquinol at night (as opposed to first thing in the morning) so that fatigue won’t impair your performance. Next post: Magnesium Deficiency Symptoms, Causes, & Treatments, Previous post: Probiotics Side Effects & Adverse Reactions (List). This site uses Akismet to reduce spam. Available for Android and iOS devices. Ubiquinol is generally very well-tolerated. Before assuming that you’re allergic to ubiquinol itself, you might want to evaluate other inactive added ingredients within the product. It also notes some case reports of allergic reactions. Headache: Among the most common ubiquinol side effects reported by users is headaches. Ubiquinol side effects for diabetic patients may decrease their insulin requirements, which could present a problem. If you’re experiencing flu-like symptoms from ubiquinol supplementation, your best bet is to immediately stop using the supplement and seek medical evaluation. Reduced levels of Ubiquinol can also affect your LDL cholesterol. If the tiredness is significant and impairing your ability to function, there’s little reason to continue supplementing with ubiquinol (unless deemed medically necessary). It should also be noted that some individuals may end up experiencing full-blown migraines, which might occur as a result of increased vasodilation (widening of blood vessels) upon introduction of ubiquinol supplementation. What likely happens is that someone taking their usual or predictable dose of an antihyperglycemic agent adds ubiquinol to his/her regimen and the ubiquinol prevents significant hyperglycemic spikes. Learn from their experiences about effectiveness, side effects and cost Examples of side effect mitigation strategies include: dosage modification or titration, altering administration details, discontinuing unnecessary substances (that might interact or synergize with ubiquinol), switching to a different brand of ubiquinol, and/or continue using ubiquinol in hopes that your body adjusts. That said, if you have any questions regarding the side effects listed above, be sure to contact a medical professional. If you’ve talked to a doctor and confirmed that ubiquinol is safe for you to take, yet are experiencing the flu-like symptoms with each administration, test a different brand (with alternative ingredients) and start with a low dose to determine whether the issue persists. Most speculate that tiredness occurring from ubiquinol supplementation may be transient and eventually subside as an individual optimizes his/her dose and continues using it for 1-2 months. If you want to continue supplementing with ubiquinol but are hung up on the sleepiness reaction, administering it at night (as opposed to first thing in the morning) may minimize daytime somnolence. Flu-like symptoms: Some medical sources report that flu-like symptoms may occur as an adverse reaction to ubiquinol supplementation. Still, any fluctuations in concentrations and/or secretions of hormones resulting from ubiquinol might provoke unexpected reactions among certain users. Additionally, after you discontinue for awhile, you can always reinstate supplementation with a low dose and/or using another ubiquinol supplement to determine if it’s more tolerable. The hypotension-induced dizziness may be more likely to occur among those with a history of high blood pressure who are simultaneously administering an antihypertensive agent (e.g. Then again, the facilitation of hormone changes by ubiquinol may be favorable in most individuals and won’t provoke side effects. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. I have been taking Ubiquinol from Mercola for over a year 100mg. Since ubiquinol can increase energy levels, it is possible that some users may end up feeling overly stimulated or activated, especially after taking a high dose. That said, it is possible that flu-like symptoms may occur from: using abnormally high or mega doses, an interaction between ubiquinol and another substance, or an allergy to one of the added ingredients. For example, you may notice onset of fatigue or experience a headache in reaction to ubiquinol supplementation, whereas another person using the same supplement might not notice any unusual reaction. There are many different brand of ubiquinol on the market, however, all of them contain Kaneka QH as the active ingredient. tree nuts, peanuts, etc. Or should I get back to take 6 *100mgs? Ubiquinol is an electron-rich, highly-bioavailable, fully reduced form of coenzyme Q10 (CoQ10) that occurs naturally within all of our cells. But started to experience insomnia and stopped taking it. If you’re experiencing palpitations, it’s best to engage in relaxation exercises (e.g. Though reducing LDL cholesterol below 40 mg/dL is highly unlikely to occur as a result of standalone ubiquinol, it’s possible that the supplemental ubiquinol may enhance reduction of LDL, leading to abnormalities. My TSH and blood pressure were great. It’s also possible that dizziness is related to an anxiogenic response that occurs among individuals taking extremely high doses or an interaction between ubiquinol and another substance you’re using. Though odds of experiencing hypoglycemia from ubiquinol are low, it is something to beware of if you’ve been diagnosed with diabetes. upset stomach, nausea, vomiting, loss of appetite; This is not a complete list of side effects and others may occur. I’m 74 and take .075 levothyroxine daily for hypothyroidism caused by 3/4 removal of thyroid gland at age 34. Celexa (Citalopram) vs. Lexapro (Escitalopram): Which Is Better? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Furthermore, in the event that you experience fatigue as a side effect of ubiquinol, realize that it may eventually diminish as your body adjusts itself to regular supplementation. This product usually has very few side effects. Results of the study indicated that follicle stimulating hormone (FSH) increased 3-fold, luteinizing hormone (LH) increased 2-fold, prolactin decreased, and progesterone appeared to increase. For this reason, most professionals recommend high doses of ubiquinol be administered along with cholesterol-reducing agents. Added ingredients: While most individuals are able to tolerate any brand of ubiquinol supplement without side effects, a subset of ubiquinol users will notice unwanted side effects and/or adverse reactions from one particular ubiquinol supplement and not another. If you’re allergic or sensitive to any of the ingredients within your ubiquinol supplement, the allergy may trigger a low-grade stress response in your body to upregulate activity in the sympathetic branch of your autonomic nervous system. There are no obvious mechanisms by which ubiquinol would make someone feel more irritable than usual, in fact, it is more likely to decrease irritability. You might want to ask your doctor about safe anxiolytics and/or hypnotics that can be used with ubiquinol to help you mitigate the insomnia reaction. In the event that you experience hypoglycemia from ubiquinol, symptoms such as: anxiety, confusion, heart palpitations, nausea, shakiness, unresponsiveness, and/or vomiting – may emerge. Those who are most prone to experiencing hypoglycemia as a side effect of ubiquinol are individuals that have been diagnosed with diabetes and/or using antihyperglycemic medications, insulin, or any glucose-lowering agents – each of which lower blood sugar. Brand + retailer: The brand of ubiquinol that you take might affect whether you experience side effects. Coenzyme Q10 is a substance found naturally in the body, supplementation of which may improve various conditions such as heart problems, macular degenration, immune fuction, diabetic neuropathy, and others. Here, you can learn the difference between Ubiquinol and Ubiquinone (known as conventional CoQ10), find the best Ubiquinol CoQ10 retail supplement brands near you, and get inspired to kick-start your heart health journey. If you happen to be allergic to one ubiquinol supplement, you may want to ask your doctor about testing another with different added ingredients to determine whether it is actually the ubiquinol OR the additives culpable for your allergic response. If you happen to experience unwanted side effects from ubiquinol, there are a few strategies you may prove helpful for side effect mitigation. Call your doctor for medical advice about side effects. Then again, you could also switch to another ubiquinol supplement with a different emulsifier and/or additives to determine whether you find other additives more tolerable than those in your current supplement. Anyone with a history of medically-diagnosed headaches and/or migraines may be most at risk of experiencing headaches as a side effect of ubiquinol. I only took one capsule and have piercing stomach pain, nausea, hot and prickly skin, and am feeling dizzy. Journaling will help provide a “big picture” perspective regarding how well you tolerate and/or function with ubiquinol over an extended duration, and catalogs all side effects for later discussion with your doctor. Based on the fact that they are using equal doses from the same manufacturer, and neither has an allergy to the ingredients, we would expect similar side effects. Quality control standards of most supplement companies are high, however, some have higher standards than others. Call your doctor for medical advice about side effects. Tiredness: Numerous anecdotal reports circulating around the internet suggest that ubiquinol can cause tiredness. Then again, the most likely cause of diarrhea from ubiquinol supplementation is a sensitivity or inability to tolerate added ingredients. Before using Ubiquinol Acetate, inform your doctor about your current list of medications, over the counter products (e.g. In most cases the side effect of appetite reduction from ubiquinol is modest, but some believe it could help with weight loss. Most of the potential side effects are mild and relate to the stomach and digestion, including nausea, diarrhea, and vomiting. Other options for managing the diarrhea include: taking ubiquinol with food (as opposed to on an empty stomach), eating fewer foods with high fiber, drinking more water, and/or trying over-the-counter Imodium. Antioxidant Effects. A small subset of individuals taking ubiquinol will report a combination of health benefit with a few minor side effects. low blood pressure. Light sensitivity 11. That said, you should always double check the ubiquinol label to ensure that you aren’t allergic to any of its constituents. Don't use CoQ10 if you're pregnant or breast-feeding. On the other hand, it’s also possible that nausea is a byproduct of other ubiquinol-induced side effects such as anxiety and/or agitation. All matters regarding your health require medical supervision. Have you tried multiple brands of ubiquinol to determine whether you’re able to tolerate one better than another? It is the interplay between these variables that explains why one user may experience zero side effects, yet another user may report an adverse reaction. morning instead of evening). That said, details of ubiquinol administration such as: dosage amount, cumulative duration and regularity of administration, and whether taken with food vs. on an empty stomach – may influence side effect severity. Fatigue: Although extremely uncommon, some persons will report fatigue and/or lethargy as a side effect of ubiquinol. Sweating: A reaction that may occur in some ubiquinol users is increased sweating. ’ ve taken ubiquinol and report any significant changes to your doctor for medical advice about side effects have., gastrointestinal upset and diarrhea, skin rashes and loss of appetite ; diarrhea ; skin rash or. Insomnia, restlessness, agitation possible allergies or sensitivities to the supplement ubiquinol side effects responsible for manufacturing your ubiquinol, ’. 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